Treatment of Osteoarthritis with Autologous and Microfragmented Adipose Tissue

After receiving a single injection of microfragmented fat, patients with knee osteoarthritis were shown to have more function, less pain, improved stiffness and other symptoms, while getting back to doing recreational and daily activities. This prospective cohort study analyzed 20 patients who had abdominal fat harvested from the abdomen, which was subsequently microfragmented, injected into the knees, and then evaluated at 3, 6, and 12 months post-injection.

The Takeaway: This limited study showed a relatively good safety profile. One patient experienced a minor cosmetic defect on the abdomen which is largely a matter of harvesting technique. Some would say this is a risk they are willing to take if they can resolve their debilitating knee osteoarthritis. Most people are more than willing to donate fat to treating their knee if it means they will have improved joint pain and function.

Barfod KW, Et Al. Treatment of osteoarthritis with autologous and microfragmented adipose tissue. Dan Med J. 2019 Oct;66(10).

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