Short-Term Outcomes of Percutaneous Trephination with a Platelet Rich-Plasma Intrameniscal Injection for the Repair of Degenerative Meniscal Lesions. A Prospective, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study
Treating a meniscus tear with platelet-rich plasma (PRP) using trephination injection techniques has shown to decrease pain, increase function, and improve symptoms while simultaneously reducing the rate of future surgical arthroscopy. 72 patients were studied in this randomized, prospective, placebo-controlled, double-blind, single-site study.
The Takeaway: It is always preferred to implement a conservative intervention that reduces the need for surgery while reducing costs, reducing risks of complications, and reducing recovery times. When performed correctly, PRP can be such an intervention. Injection technique is more important than what is being injected. This article describes an injection technique called trephination which is designed to create a mild injury to the targeted tissues to stimulate a therapeutic response. To get the best outcomes, an expert like Dr. Silva will utilize the indicated orthobiologic (such as PRP or stem cells, etc.) at the appropriate concentration, precisely placing the needle (the delivery method for the orthobiologic) into the affected tissues using ultrasound or fluoroscopic (x-ray) guidance, and proper injection techniques like trephination.
Kaminski R, Et Al. Short-Term Outcomes of Percutaneous Trephination with a Platelet Rich Plasma Intrameniscal Injection for the Repair of Degenerative Meniscal Lesions. A Prospective, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study. Int J Mol Sci. 2019 Feb 16;20(4).