Platelet-rich plasma versus hyaluronic acid in the treatment of knee osteoarthritis: a meta-analysis
Twenty randomized control trials were reviewed in this study and found PRP injections into the knee to be better than hyaluronic acid injections when treating knee osteoarthritis. Both pain and function were improved in the short term and long term without increased risk of adverse events.
The Takeaway: Hyaluronic acid is usually the other treatment that doctors will offer when cortisone injections don’t help. Now we can see that there is another option, PRP, that is superior to both cortisone and hyaluronic acid without increasing the risk of side effects.
Tang JZ, Nie MJ, Zhao JZ, Zhang GC, Zhang Q, Wang B. Platelet-rich plasma versus hyaluronic acid in the treatment of knee osteoarthritis: a meta-analysis. J Orthop Surg Res. 2020 Sep 11;15(1):403.