Efficiency of Platelet-Rich Plasma Therapy in Knee Osteoarthritis Does Not Depend on Level of Cartilage Damage

Treating knees with Platelet-rich plasma (PRP) found that symptoms improved regardless of the severity of knee osteoarthritis. 59 patients had their knee osteoarthritis graded by MRI using 14 different grading characteristics. After multivariant analysis, symptomatic improvement did not correlate with the severity grade of osteoarthritis.

The Takeaway: This is a great study that illustrates the idea that regardless of the stage of joint degeneration (mild to very severe), the overall condition of arthritic joints can still be improved upon with PRP injections. For example, even the most severe cases of “bone on bone” osteoarthritis still benefit from comprehensive PRP treatments through reduced pain and improved function. There are many factors that contribute to this phenomenon and an evaluation at IOW can help you identify your potential benefit.


Burchard R, Et Al. Efficiency of platelet-rich plasma therapy in knee osteoarthritis does not depend on level of cartilage damage. J Orthop Surg Res. 2019 May 24; 14 (1):153.

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