Effect of Autologous Platelet Leukocyte Rich Plasma Injections on Atrophied Lumbar Multifidus Muscle in Low Back Pain Patients with Monosegmental Degenerative Disc Disease

104 patients with chronic low back pain had 6 weekly injections of leukocyte-rich platelet-rich plasma (LR-PRP) into weak muscles of the lumbar spine at the level of degenerative disc disease. Improvement of low back pain and function was noted at 12 months post-injection, improvement climaxed at 18 months but continued to benefit patients at 24 months. MRI performed at 12 months post-injection noted increased muscle bulk with decreased fatty atrophy of the lumbar multifidus muscles.

The Takeaway: Weak lumbar multifidus muscles are correlated with chronic low back pain. Dr. Silva always treats the muscles of the low back as part of a comprehensive cellular lumbar treatment plan. He takes a functional approach to treatment, meaning he treats all aspects of the spine that contribute to pain and dysfunction, which may include muscles, ligaments, capsules, facet joints, discs, bones or nerves. Rarely, if ever, is low back pain the result of a single pain generator or a single dysfunctional component. PRP can be made to varying concentrations of platelets and/or cells, and it is important that injectates (such as PRP) are adjusted precisely to meet the needs of the specific degenerative tissues. If you find yourself stuck with low back pain after seeing various doctors and you are facing the real possibility of surgery, schedule an appointment with Dr. Silva to see if he can help you get back to doing the things you love.

Hussein M, Et Al. Effect of autologous platelet leukocyte rich plasma injections on atrophied lumbar multifidus muscle in low back pain patients with monosegmental degenerative disc disease. SICOT J. 2016 Mar 22;2:12

Book Appointment