Functional Outcomes Following Microfragmented Adipose Tissue Versus Bone Marrow Aspirate Concentrate Injections for Symptomatic Knee Osteoarthritis

Bone marrow concentrate (BMC) was compared to microfragmented adipose in treating knee osteoarthritis and found that both types improved pain, stiffness, activities of daily living, sports, function, quality of life and other symptoms in 110 patients with knee osteoarthritis Kellgren Lawrence grades 1, 2, 3, and 4.

The Takeaway: Both BMC and adipose have powerful mesenchymal stem cells (MSCs) which can support tissue healing. MSCs from bone marrow are freely available while MSCs from adipose are sequestered by collagen and require a process to free up the cells commonly done via microfragmentation or enzymatic release. If you happen to have some fat to spare, it’s quite possible to use it to treat your orthopedic conditions.

Reference:
Mautner K, Et Al. Functional Outcomes Following Microfragmented Adipose Tissue Versus Bone Marrow Aspirate Concentrate Injections for Symptomatic Knee Osteoarthritis. Stem Cells Transl Med. 2019 Nov;8(11):1149-1156

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